"Too much estrogen can lead to irregular, heavy periods, weight gain, problems sleeping, fatigue, depression or irritability, and a low libido," says Cheung. Helps mitigate estrogen dominance: Cheung notes that estrogen dominance can result from poor liver detoxification or obesity, as fat tissue will metabolize testosterone into estrogen. External factors such as birth control, excess meat and dairy, plastics, and other toxins may also contribute to estrogen dominance and resulting symptoms.I3C is the precursor to DIM, which is formed naturally. It’s known to stimulate detoxifying enzymes in the gut and liver, and most importantly, it regulates estrogen and androgen. DIM supplements also are available from many retail sources and might help prevent or suppress growth of several forms of cancer, including. "Since DIM balances estrogen metabolism and receptor activity, and stimulates cellular detoxification, it may help support the prevention of various cancers, including breast, uterine, cervical, and prostate cancers," says Cheung. Indole 3-Carbinol, also known as I3C, is a naturally-resulting compound that comes from eating cruciferous vegetables such as broccoli, cauliflower, and cabbage. Diindolylmethane, or DIM, is a natural chemical formed in your digestive tract from a compound called glucobrassicin, which is contained in cruciferous vegetables such as broccoli, cauliflower and cabbage. May prevent estrogen cancers: Taken as a supplement, I3C studies are increasingly showing its potential strength in preventing the development of estrogen-enhanced cancers.DIM and I3C help to maintain this delicate balance, and higher levels of DIM will block androgen pathways to decrease sebum production and acne," she explains. "Hormonal acne results from an imbalance of estrogens and testosterone. DIM Detox promotes healthy cell cycle function and hormone metabolism to support the livers natural detoxification process. (Diindolylmethane) SubtitlesDIM is a chemical which is made naturally in the body when we consume crucifer. DIM may help relieve PMS symptoms caused by fluctuating estrogen. Though there's no scientific evidence that DIM supplements fix or cure hormonal acne, Cheung says they can help. The health benefits of DIM in males and females. DIM inhibits aromatase, so that more testosterone is freely available in your system to benefit your heart, bones, skin, and brain. Women may benefit from taking DIM supplements in several ways. Clears hormonal acne: Hormonal acne appears primarily on your chin and jawline, but can occur on the sides of your face and down your neck as well. Dimensions of Dental Hygiene is a monthly, peer-reviewed journal that reconnects practicing dental hygienists with the nations leading.*Indole-3-cabinol (I3C) and diindolylmethane (DIM) contained in this product are synthetic duplicates, not naturally sourced. As a dimer (formed chemical structure of two substances) of indole-3-carbinol, DIM promotes beneficial estrogen metabolism in both sexes supporting the formation of healthy estrogen metabolites. A study published in the Journal of Nutrition unveiled evidence that I3C supports healthy cellular function related to estrogen metabolism.ĭIM is a phytonutrient and plant indole also found in cruciferous vegetables. I3C has also been shown to temper estrogen signals by competing for binding sites and inhibiting the activity of estrogen receptors. Both of these compounds, as well as many other I3C metabolites, have been shown to impact metabolic shifts and cellular activities for improved health outcomes. Compare to other brands that only give you 100mg - 250mg per capsule.
In a Canadian clinical study, women taking DIM showed an increase in BRCA1 expression a gene and its protein which can help inhibit breast cancer by 34. EXTRA STRENGTH DIM: DIM Plus 300mg pure DIM per capsule ensures you get all you need in just one serving (2 month supply). Dark urine (pink to orange to brownish) The consensus is that darkened urine is harmless and will return to normal once you stop taking your DIM supplement. DIM research DIM has some strong evidence behind its use to potentially reduce the risk of serious conditions, including breast and cervical cancer.
Following ingestion of I3C, the body converts it to several different metabolites, one of which is diindolylmethane (DIM). DIM is generally well-tolerated with a few mild symptoms for a few days. I3C is a naturally occurring compound found in numerous cruciferous vegetables, such as broccoli, cauliflower, kale and cabbage.